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    Molekulare Biotechnologie

    Konzepte und Methoden

    Molekulare Biotechnologie
    Konzepte und Methoden

    Verlag:
    Wiley-VCH   Weitere Titel dieses Verlages anzeigen

    Auflage: 2. völlig neu überarbeitete Auflage
    Erschienen: Januar 2011
    Seiten: 654
    Sprache: Deutsch
    Preis: 87.90 €
    Illustration: 200 farbige Abbildungen, 100 schwarz-weiße Tabellen
    Maße: 284x215x37
    Einband: Taschenbuch
    ISBN: 9783527326556

    Inhaltsverzeichnis

    GRUNDLAGEN DER ZELL- UND MOLEKULARBIOLOGIE Die Zelle ist die Grundeinheit des Lebens (M. Wink) Aufbau und Funktion der zellulären Makromoleküle (M. Wink) Struktur und Funktion der Zelle (M. Wink) Biosynthese und Funktion der Makromoleküle (DNA, RNA und Proteine) (M. Wink) Verteilung der Proteine in der Zelle (Protein Sorting) (M. Wink) Evolution und Diversität der Organismen (M. Wink) STANDARDMETHODEN DER MOLEKULAREN BIOTECHNOLOGIE Isolierung und Reinigung von Proteinen (T. Wieland, M. Lutz) Peptid- und Proteinanalytik mit Elektrospray-Tandem-Massenspektrometrie (A. Schlosser, W.D. Lehmann) Isolierung von DNA und RNA (H. Weiher, R. Zwacka, I. Herr) Chromatographie und Elektrophorese von Nucleinsäuren (H. Weiher, R. Zwacka, I. Herr) Hybridisierung von Nucleinsäuren (H. Weiher, R. Zwacka, I. Herr) Enzyme zur Modifikation von Nucleinsäuren (A. Groth, R. Zwacka, H. Weiher, I. Herr) Polymerase-Kettenreaktion (PCR) (A. Mohr, H. Weiher, I. Herr, R. Zwacka) Sequenzierung von DNA (R. Zwacka, A. Mohr, I. Herr, H. Weiher) Klonierungsverfahren (T. Wieland, S. Lutz) Expression rekombinanter Proteine (T. Wieland, S. Lutz) Patch-Clamp-Technik (R. Kraft) Zellzyklusmessungen (S. Wölfl, A. Kitanovic) Mikroskopie-Techniken (S. Diekmann) Laseranwendungen (M. Vogel, R. Fink) SCHWERPUNKTTHEMEN DER MOLEKULAREN BIOTECHNOLOGIE Genomik und Funktionelle Genomik (S.Wiemann, M. Frohme) Bioinformatik (B. Brors) Zelluläre System-Biologie (R. König, B. Brors, H. Schmidt-Glenewinkel, S. Legewie) Protein?Protein- und Protein?DNA-Interaktionen (P. Uetz, E. Pohl) Wirkstoffforschung (M. Koegl, R. Tolle, U. Deuschle, C. Kremoser) Drug Targeting und Prodrugs (G. Fricker) Molekulare Diagnostik in der Medizin (S. Wölfl, R. Gessner) Rekombinante Antikörper und Phagen-Display (S. Dübel) Genetisch veränderte Mäuse (Transgene und Knock(in)out-Mäuse) und deren Bedeutung in der Biomedizin (R. Sprengel) Gentherapie: Strategien und Vektoren (A. Groth, I. Herr) Modifizierte DNA, PNA und ihre Anwendungen in der Medizin und Biotechnologie (N. Metzler-Nolte, A. Sosniak) Pflanzliche Biotechnologie (H. Hillebrand, R. Hell) Biokatalyse in der chemischen Industrie (M. Breuer, B. Hauer) WIRTSCHAFTLICHE PERSPEKTIVEN DER MOLEKULAREN BIOTECHNOLOGIE Industrielle Umsetzung (Biotech-Industrie, Märkte und Chancen) (J. Schüler) Patente und Schutz von Ideen (C. Amshoff) Zulassung von Arzneimitteln in der Europäischen Union und den Vereinigten Staaten (G. Walsh) Zusammenspiel zwischen Big Pharma und Biotech-Start-up-Unternehmen (C. Kremoser) Das kleine 1x1 der Firmengründung (C. Kremoser) Glossar (M. Wink) Weiterführende Literatur Abkürzungen