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/web/Sites/BlickinsBuch.de/functions.php on line 241 Warning: preg_replace(): Compilation failed: this version of PCRE is not compiled with PCRE_UTF8 support at offset 0 in /web/Sites/BlickinsBuch.de/functions.php on line 241 Warning: preg_replace(): Compilation failed: this version of PCRE is not compiled with PCRE_UTF8 support at offset 0 in /web/Sites/BlickinsBuch.de/functions.php on line 241 Warning: preg_replace(): Compilation failed: this version of PCRE is not compiled with PCRE_UTF8 support at offset 0 in /web/Sites/BlickinsBuch.de/functions.php on line 241 Warning: preg_replace(): Compilation failed: this version of PCRE is not compiled with PCRE_UTF8 support at offset 0 in /web/Sites/BlickinsBuch.de/functions.php on line 241 Warning: preg_replace(): Compilation failed: this version of PCRE is not compiled with PCRE_UTF8 support at offset 0 in /web/Sites/BlickinsBuch.de/functions.php on line 241 Warning: preg_replace(): Compilation failed: this version of PCRE is not compiled with PCRE_UTF8 support at offset 0 in /web/Sites/BlickinsBuch.de/functions.php on line 241 Warning: preg_replace(): Compilation failed: this version of PCRE is not compiled with PCRE_UTF8 support at offset 0 in /web/Sites/BlickinsBuch.de/functions.php on line 241 Warning: preg_replace(): Compilation failed: this version of PCRE is not compiled with PCRE_UTF8 support at offset 0 in /web/Sites/BlickinsBuch.de/functions.php on line 241 Warning: preg_replace(): Compilation failed: this version of PCRE is not compiled with PCRE_UTF8 support at offset 0 in /web/Sites/BlickinsBuch.de/functions.php on line 241 Warning: preg_replace(): Compilation failed: this version of PCRE is not compiled with PCRE_UTF8 support at offset 0 in /web/Sites/BlickinsBuch.de/functions.php on line 241 Warning: preg_replace(): Compilation failed: this version of PCRE is not compiled with PCRE_UTF8 support at offset 0 in /web/Sites/BlickinsBuch.de/functions.php on line 241 Warning: preg_replace(): Compilation failed: 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/web/Sites/BlickinsBuch.de/functions.php on line 241 Warning: preg_replace(): Compilation failed: this version of PCRE is not compiled with PCRE_UTF8 support at offset 0 in /web/Sites/BlickinsBuch.de/functions.php on line 241 Warning: preg_replace(): Compilation failed: this version of PCRE is not compiled with PCRE_UTF8 support at offset 0 in /web/Sites/BlickinsBuch.de/functions.php on line 241 Warning: preg_replace(): Compilation failed: this version of PCRE is not compiled with PCRE_UTF8 support at offset 0 in /web/Sites/BlickinsBuch.de/functions.php on line 241 Warning: preg_replace(): Compilation failed: this version of PCRE is not compiled with PCRE_UTF8 support at offset 0 in /web/Sites/BlickinsBuch.de/functions.php on line 241 Warning: preg_replace(): Compilation failed: this version of PCRE is not compiled with PCRE_UTF8 support at offset 0 in /web/Sites/BlickinsBuch.de/functions.php on line 241 Warning: preg_replace(): Compilation failed: this version of PCRE is not compiled with PCRE_UTF8 support at offset 0 in /web/Sites/BlickinsBuch.de/functions.php on line 241 Warning: preg_replace(): Compilation failed: this version of PCRE is not compiled with PCRE_UTF8 support at offset 0 in /web/Sites/BlickinsBuch.de/functions.php on line 241 Blickinsbuch.de - GENial! - Ernst Peter Fischer
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    GENial!

    Was Klonschaf Dolly den Erbsen verdankt - Ein Streifzug durch die Genetik

    GENial!
    Was Klonschaf Dolly den Erbsen verdankt - Ein Streifzug durch die Genetik

    Autoren:

    Verlag:
    Herbig Verlag  Weitere Titel dieses Verlages anzeigen

    Erschienen: März 2012
    Seiten: 349
    Sprache: Deutsch
    Preis: 9.99 €
    Illustration: mit Abbildungen
    Maße: 212x138x38
    Einband: Gebundene Ausgabe
    ISBN: 9783776626841

    Inhaltsverzeichnis

    Vorwort
    Genetisch kommt von Goethe7
    Der Physiker im Klostergarten
    Gregor Mendel und die Gesetze der Vererbung18
    Der erste Blick auf die Gene
    William Bateson, Carl Correns, Archibald Garrod,
    Wilhelm Johannsen41
    Die Ankunft einer Fliege
    Thomas Hunt Morgan und seine Schule führen
    die Fliege Drosophila ein66
    Die Moleküle des Lebens
    Die Biochemiker und der Weg
    zur Ein-Gen-ein-Enzym-Hypothese97
    Das Atom der Biologie
    Max Delbrück & Co. begründen die
    Molekularbiologie115
    Ein Gefühl für den Organismus
    Barbara McClintock -
    eine Frau in der Männerwelt136
    14
    Am Faden des Lebens
    J. D. Watson, F. Crick und andere erkennen
    die Struktur des Erbmaterials...........
    Revolution in der Molekularbiologie
    Der genetische Code, die Synthese der Proteine,
    das Dogma der Molekularbiologie und
    die Regulation der Gene174
    Eine neue Technik bringt eine neue Genetik
    Werner Arber, Herbert Boyer, Paul Berg und
    die Faszination des Klonens206
    Die Auskunft einer Fliege
    Seymour Benzer und andere, die Verhalten
    und Genetik zusammendenken wollen241
    Hello Dolly - Vom kurzen Leben eines berühmten
    Schafes
    Über einige Grenzen der genetischen Eingriffe270
    Tausendundein Genom und mehr
    Walter Gilbert, Craig Venter, Francis Collins &
    Co. knöpfen sich die Genome vor285
    Nachwort
    Der genetische Stand der Dinge322
    Anhang
    Zeittafel331
    Ausgewählte Literatur334
    Glossar337
    Register344

    Register

    Adaptor-Hypothese 194 f.
    Allele 22, 43 f.
    Alpha-Helix 150
    Aminosäuren 108, 112, 177 f., 180, 186, 189 f., 199 f., 224, 233, 255
    Antigen 228, 230 f., 233
    Antikörper 228 f., 230 ff.
    Arber, Werner 207 ff., 234
    Asilomar-Konferenz 219
    Astbury, William 158 f.
    Atome 27, 34 f., 38 f., 101 ff., 116 ff., 122 ff., 159, 185, 242, 296, 315, 328
    Atomkern 118, 328
    Atomverband 15, 101, 121, 153
    Avery, Oswald 113, 133
    Bakteriophagen 124 ff., 143, 161, 184, 207, 242
    Baltimore, David 220
    Bandenmuster 88
    Basenpaare 165, 167 ff., 178 ff., 199, 214, 222, 243, 256, 292 f., 306, 308, 328
    Bateson, William 14, 30, 43,
    46 ff., 50, 57, 59, 62, 66, 252 f.
    Beadle, George 106, 109
    Bell, Florence 158
    Benzer, Seymour 184 f., 241 ff.,
    244 ff.
    Berg, Paul 220, 227
    Bermuda-Prinzipien 304
    Biokatalysatoren 105
    Biosynthese 179
    Bohr, Niels 117 ff., 122
    Boten 179, 188, 191,246 f.
    Boten-RNA (mRNA) 191, 323
    Botenmolekül 179, 221, 226
    Botstein, David 236, 290
    Boyer, Herbert 215
    Bragg, William 150 f.
    Brenner, Sydney 191, 248 f.
    Bresch, Carsten 192
    Bridges, Calvin 80 f., 87 f.
    Brosius, Jürgen 184
    Buchner, Eduard 98 ff.
    California Institute of Technology (Caltech) 92, 121 ff., 169 f., 243
    Castle, William E. 68 f.
    Cavendish Laboratory 149 ff., 150, 153
    Chargaff, Erwin 165 f.
    Chase, Martha 134 f., 163
    Chromatin 56
    Chromosomen des Menschen 54 f., 309
    Chromosomentheorie 73
    Chromosomfaden 143
    Cistron 184
    Cluster 260
    Cochran, William 166
    Code, genetischer 156, 178, 180, 182 f., 189, 199 ff., 205, 225
    Coen, Enrico 267
    Cohen, Daniel 299
    Cohen, Stanley 215
    Cold Spring Harbor Laboratory (CSHL) 70
    Collins, Francis 303 f., 306 f., 311
    copy DNA (cDNA) 221, 223
    Correns, Carl 41 ff., 45, 66, 76
    Creighton, Harriet 140
    Crick, Francis H. C. 146 f., 149 ff., 161, 164 ff., 169, 172, 176, 188 ff., 205, 220, 241, 245, 326
    Crossing over 81, 140
    Darwin, Charles 28, 47, 49, 94,
    130 f.
    Davis, Ronald W. 236, 290
    de Vries, Hugo 41, 58
    Degradation 177
    Delbrück, Max 15, 91, 116 ff., 125 ff., 144, 152 f., 169 f., 242, 245
    Desoxyribonukleinsäure (DNS) 111, 147
    Diauxy-Phänomen 194
    Diversität 93
    DNA, kodierende 225
    DNA, repetitive 301, 309
    DNA-Bausteine 178, 180, 185, 199, 255
    DNA-Fäden 87, 212 f., 263
    DNA-Fragmente 210, 213, 294
    DNA-Moleküle 174 f., 208 f., 212 f., 222, 235, 294, 325
    DNA-Schäden 289
    DNA-Sequenzen 13, 184, 196,
    198 f., 212, 225, 256, 271,
    288,295, 300, 309, 313 f.
    DNA-Struktur 169, 173, 199, 205
    Dobzhansky, Theodosius 92 ff.
    Domäne 229 ff., 258
    Dominant 23 f., 43 ff., 76
    Donohue, Jerry 166
    Dopingmittel 216
    Doppelhelix 146 ff., 155, 167 ff., 174, 176, 178, 172, 174, 176, 178, 186, 188, 209 ff., 221 f., 299, 306
    Dounce, Alexander 186
    Dulbecco, Renato 220, 234, 286, 289, 292
    Dunn, Leslie 15
    Ein-Exon-eine-Domäne-Hypo- these 100
    Ein-Gen-ein-Enzym-Hypothese 100, 108 f., 183
    Ein-Gen-ein-Polypeptid-Hypo- these 191, 226
    Ellis, Emory 122 f., 125
    Embryo 33, 232, 251, 262
    Embryologie 68, 156
    Embryonalentwicklung 251, 257, 265
    Enhancer 225
    Enzyme 99 f., 102 f., 105 f., 109, 112, 174 f., 178, 198,212, 325
    Epigenetik 8, 316 ff.
    Epigenome 316
    Erbanlagen 32, 43, 46 f., 51, 54, 58, 63, 82, 94, 123, 248, 285
    Erbgesetze 19, 48
    Erbelemente 14, 22 ff., 33, 35, 38, 43, 49, 57 f., 75
    Erbfaktoren 12, 38, 47, 75, 78, 142
    Erbkrankheiten 18, 29, 62, 304
    Erblichkeitslehre 58 f., 60
    Erbmaterial 88, 93 f., 124, 126, 142, 144, 155, 162, 172, 210, 221 f., 252, 293,316,318
    European Molecular Biology Laboratory (EMBL) 187
    Evolution 20, 47 f., 50, 94 ff.,
    226, 249 ff., 259, 265, 268,
    272, 288, 309 f.
    Exon 225 f., 229 ff.
    Farbenblindheit 32, 61, 78
    Fermentation 98 f.
    Filialgeneration 22 f.
    Fingerabdruck, genetischer
    237 f.
    Flemming, Walther 56 f.
    Fluktuationstest 132
    Franklin, Rosalind 164 f.
    Garrod, Archibald 61 ff.
    Gedächtnis 206, 247
    Gedächtnis der Gene 318, 321
    Gehring, Walter 249, 251, 261
    Gendiagnose 8
    Gene, homöotische 46 f., 252 ff.,
    258 ff.
    Genetik, neue 28, 119, 227, 236, 287, 291
    Genforschung 10, 285, 303
    Genkarte (genetische Karte) 83, 85, 236 f., 243, 290 f., 295
    Genkopplung 42
    Genlocus 141
    Genmanipulation 213, 227
    Genmutation 91, 115 f., 130, 152
    Genom 143 ff., 173, 214, 251, 265, 285 ff., 292, 294, 297 ff., 304 ff., 309 ff., 316 f., 322 f., 330
    Genomforschung 285, 298 ff., 303,312
    Genomprojekt 63, 239, 309, 312
    Genotyp 61, 325
    Genpool 94, 310
    Genprodukte 216, 263
    Gensequenz 12, 240, 263, 271,
    300, 313, 317, 322 f.
    Genstruktur 115 f., 224
    Genstücke 222, 231 f.
    Gentechnik 12, 205, 209, 213 ff., 217 ff., 228 f., 235 f., 256, 271, 273, 286, 289, 291, 294
    Gentechnologie 276
    Gentransfer 309
    Gilbert, Walter 227, 294 ff.
    Gosling, Raymond 164
    Gould, Stephen J. 184
    Hefezellen 98 f., Hershey, Alfred 132 ff., 163
    Hershey-Chase-Experiment
    134 f.
    Homöobox 249 f., 252, 255 f., 258 f., 261, 269
    Homöodomäne 255, 259
    Homöose 46
    Hood, Leroy 234 f.
    Hoppe-Seyler, Felix 52
    Hormone 104, 178, 216, 246, 325
    Humangenetik 9
    Humangenom 239, 301
    Individualität 9, 11 f., 63 f., 217, 235, 237
    Information, genetische 7, 13,
    140, 155, 173, 183, 186,
    188 f., 191 f., 209,218, 225,
    229, 255, 300, 314, 316 f.
    Informationsträger 189
    Insulin 176 ff., 180 f., 216, 227
    Intron 225 f., 231
    In-vitro-System 186 f., 200
    J. Craig Venter Institute 300
    Jacob, François 163, 188, 191, 194, 196, 202 ff., 261
    Jeffreys, Alec 237
    Johannsen, Wilhelm 12, 15, 58 ff., 78, 99
    Keimbahn 90, 140, 273
    Kendrew, John 153
    Kieckhefer Foundation 157
    Kitcher, Philip 15, 285
    Klibansky, Raymond 262
    Klon 214 f., 282, 294
    Klonen 214 f., 265, 270, 272 f.,
    275 ff., 282 f.
    Klonschaf 270, 273 f.
    Konsensus-Sequenz 310 f.
    Kontrollelemente 142 ff.
    Kossei, Albrecht 102 f., 110 f.
    Kreativität 145, 264 ff., 268 ff.
    Krebs 13, 286 ff., 291, 297, 300, 320, 323
    Krebszellen 7, 55, 287
    Kreuzungen 18 f., 41 ff., 48, 59, 83 f., 88, 92,115, 122
    Lamarck, Jean-Baptiste de 130
    Luria, Salvatore E. 129 ff., 144, 150
    Lwoff, André 194
    Mach, Ernst 38
    Makromoleküle 103 ff., 109, 112,153,174 f., 177
    Master-Proteine 266 f., 269
    Matthaei, Heinrich 200 f.
    McClintock, Barbara 136 ff.
    Medical Research Council (MRC) 153
    Medikamente 216, 297, 300
    Mendel, Gregor 10, 12 ff., 18 ff., 23, 25 ff., 37, 39 f., 42 ff., 48 f., 71 ff., 76 f., 99, 142, 245
    Mendelismus 38, 75
    Mendelsche Regeln 22 ff., 42, 44
    messenger RNA (mRNA) 16, 179 f., 188, 191,197, 221, 222, 226, 233, 323
    Methylierung 318 f.
    Miescher, Friedrich 51 ff., 55, 102
    Mikrobiologie 126
    Mitose 57
    Molekularbiologie 10, 25, 29, 100, 106, 116, 121, 124, 126, 129, 151, 153, 155 f., 159 f., 172 f., 175 f., 181 f., 187, 189, 192 ff., 201 f., 205 f., 216, 219 f., 241, 296, 326, 328
    Molekulargenetik 123, 205
    Moleküle 11,36, 102 f., 144,
    150, 154, 156, 159, 174 f.,
    177 f., 181,206,213, 237,
    246, 253, 270, 287 f., 317,
    319, 329 f.
    Monod, Jacques 188, 191, 194,
    196, 201 ff.
    Morgan, Thomas H. 10, 25, 70 ff., 75 ff., 87 f., 91 ff., 97, 121, 139, 290
    Mosaikgen 225 f., 255
    Mosaikstruktur 225, 230 f., 308
    Muller, Hermann 15, 80, 88 ff., 103, 120
    Müller-Hill, Benno 296
    Mullis, Kary 238 f.
    Mutation 119 ff., 130, 184, 189, 253,288
    Muton 184
    National Center for Human Ge- nome Research (NCHGR) 299
    Neurogenetik 243, 245
    Neuronen 247
    Neurotransmitter 246
    Nirenberg, Marshall 200 f.
    Nukleinsäuren 53, 55, 102 f., 110 ff., 126, 133, 135, 143, 158, 161, 165, 180 f., 184
    Nukleotide 112, 158, 165, 178 f.
    Nukleus (Nucleus), vgl. Zellkern Nuon 184
    Onkogene 218, 287 f.
    Operator 196 ff.
    Operon 196 ff.
    Pardee, Arthur 188
    Parentalgeneration 22
    Pauling, Linus 150, 158, 170
    Permease 198
    Perutz, Max 150, 153
    Phänotyp 60 f., 325
    Poisson, Simeon Denis 127 f.
    Poisson-Verteilung 127
    Polymerase 198, 238
    Polymerasekettenreaktion (PCR)
    215, 238 f.
    Polymorphismus 236, 290 f.
    Polypeptid 190, 200
    Portmann, Adolf 284
    Primärstruktur 188 ff., 263
    Programm, genetisches 261 ff., 270, 274
    Promotor 196 ff.
    Proteinbausteine 178, 180, 255, 263
    Proteine, Synthese von 155, 175, 179, 186, 188, 193, 323
    Protoplasma 55
    Recon 184
    Regulation, genetische 195 ff., 201
    Regulatorgene 196, 199
    Rekombination 83, 184, 190, 213, 232, 243
    Replikation 125
    Repressor 196 f.
    Reproduktion 31, 279
    Restriktionsenzyme 212 ff., 289
    Retroviren 221
    Rezessiv 23 f., 43 ff., 62, 76, 79
    RFLP (Riflip) 290 f., 299
    Ribosom 179
    Riesenchromosomen 87 f.
    RNA-Interferenz 324
    RNA-Moleküle 180, 226, 323 ff.
    Roberts, Richard 223
    Röntgenstrahlen 89 ff., 103, 109, 120, 150, 153, 159, 161
    Rückkopplung 198 f.
    Salk-Institut 156 f.
    Sanger, Frederick 176 ff., 180 f., 227
    Schrödinger, Erwin 152 f., 170, 185, 242
    Seele 157, 162, 276 f., 282 f., 321
    Selektion 47, 93 f.
    Sequenzhypothese 189
    Sequenzierung 227, 289, 293 f., 296, 298, 300
    Sharp, Phillip 220 ff.
    Spaltungsregel 23, 43
    Spezifität 178, 182, 186, 189 f., 230, 233
    Spleißen 226, 233 f.
    Staudinger, Hermann 102 f.
    Stent, Gunther 205
    Stoffwechsel 105 ff., 153, 176, 195 f., 198, 208, 246, 296
    Stoffwechselkrankheit 62
    Stoffwechselstörungen 61, 63
    Strukturgene 196 f., 199, 224
    Sturtevant, Alfred 80 f., 83 ff., 290
    Sutton, Walter 73 f.
    Tatum, Edward Lawrie 106,
    108 f.
    Telomere 55, 320
    Temin, Howard 220
    The Institute for Genomic Research (TIGR) 300
    Timofeef-Ressovsky, Nikolai 91, 120
    Tonegawa, Susumu 234 f.
    Transfer-RNA (tRNA) 180, 323
    Transformationsprinzip 114
    Transkriptase 221
    Transkription 179, 198, 221, 224, 226
    Translation 180, 226
    Triplett 180,199 f.
    Tumorgene 218 f.
    Tumor-Suppressor-Gen 287 f.
    Umwelt 7 f., 13, 59 f., 130, 228, 265, 279 f., 318
    Umweltfaktoren 75
    Venter, Craig 298, 300 ff., 315, 318
    Wachstum, sekundäres 129 f.
    Waddington, Conrad 316 f.
    Waldeyer, Heinrich Wilhelm 56
    Watson, James D. 15 f., 146 ff., 154, 158 ff., 169 ff., 176, 192, 205, 299, 303
    Weismann, August 89 f.
    Weissenbach, Jean 299
    Wilkins, Adam S. 268
    Wilkins, Maurice 163 f.
    Winnacker, Ernst-Ludwig 16
    Zamecnik, Paul 186
    Zellkern 51, 53, 56, 61, 147, 174, 312
    Zellteilung 55 ff., 289
    Zimmer, Karl Günter 120
    Zwischenträger 155, 186, 188 f.,
    191 f.
    Zytogenetik 139